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Commonly in liquid form and available in various chemical compositions, solvents are substances that dissolve solutes to form solutions. The amount and type of solute that a solvent can dissolve is dependent upon temperature and polarity.
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Eugenol-d3 is the deuterium labeled Eugenol. Eugenol is an essential oil found in cloves with antibacterial, anthelmintic, and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Propofol-d17 β-D-glucuronide is a deuterium-labeled internal standard of propofol β-D-glucuronide suitable for use as a tracer or quantitative reference in NMR, GC-MS, and LC-MS analyses. It is supplied as a high-purity isotopologue for metabolite quantitation and method development.
Deuterium-labeled propofol β-D-glucuronide for use as an internal standard
High purity: 98.0%
Available in small quantities including 1 mg
Soluble in ethanol, DMF, and DMSO at ≥ 30 mg/mL
Powder: store at -20°C; in solvent: -80°C (6 months) or -20°C (1 month)
Suitable for NMR, GC-MS, and LC-MS quantitative analysis
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Monomethyl auristatin E-d8 (MMAE-d8) is a deuterated labeled monomethyl auristatin E, functioning as a potent mitotic inhibitor and tubulin inhibitor. It is utilized in antibody-drug conjugates (ADC) as a cytotoxic payload and can serve as a tracer or internal standard for quantitative analysis.
Potent mitotic and tubulin inhibitor
Used in antibody-drug conjugates (ADC) as a cytotoxic payload
Can be used as a tracer
Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Targets microtubule/tubulin and ADC cytotoxins
Relevant to cell cycle/DNA damage, cytoskeleton, and antibody-drug conjugate related research
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An SPHK1 inhibitor (IC50 = 0.5 µM for non-ATP-competitive inhibition of human recombinant SPHK1); selective for SPHK1 over ERK2, PI3K, and PKCα at 50s = 0.9-4.6 µM)
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